Clay B. Siegall: search on Z-Library

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1

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

Doronina, Svetlana O, Toki, Brian E, Torgov, Michael Y, Mendelsohn, Brian A, Cerveny, Charles G, Chace, Dana F, DeBlanc, Ron L, Gearing, R Patrick, Bovee, Tim D, Siegall, Clay B

Journal:

Nature Biotechnology

Year:

2003

Language:

english

File:

PDF, 254 KB

english, 2003

2

Cytotoxic Activity of an Interleukin 6--Pseudomonas Exotoxin Fusion Protein on Human Myeloma Cells

Clay B. Siegall, Vijay K. Chaudhary, David J. FitzGerald and Ira Pastan

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 877 KB

english, 1988

3

Immunotoxins as cancer chemotherapeutic agents

Clay B. Siegall, Edith A. Wolff, Susan L. Gawlak, Leland Paul, Dana Chace, Bruce Mixan

Journal:

Drug Development Research

Year:

1995

Language:

english

File:

PDF, 959 KB

english, 1995

4

In Vivo Efficacy and Toxicity of a Single-Chain Immunotoxin Targeted to CD40

Francisco, Joseph A., Schreiber, George J., Comereski, Chuck R., Mezza, Laurence E., Warner, Garvin L., Davidson, Thomas J., Ledbetter, Jeffrey A., Siegall, Clay B.

Journal:

Year:

1997

File:

PDF, 221 KB

1997

5

Expression and Characterization of Bryodin 1 and a Bryodin 1-Based Single-Chain Immunotoxin from Tobacco Cell Culture

Francisco, Joseph A., Gawlak, Susan L., Miller, Michael, Bathe, Jessie, Russell, David, Chace, Dana, Mixan, Bruce, Zhao, Lei, Fell, H. Perry, Siegall, Clay B.

Journal:

Bioconjugate Chemistry

Year:

1997

Language:

english

File:

PDF, 175 KB

english, 1997

6

Targeted therapy of carcinomas using BR96 sFv-PE40, a single-chain immunotoxin that binds to the Leyantigen

Clay B. Siegall

Journal:

Seminars in Cancer Biology

Year:

1995

Language:

english

File:

PDF, 88 KB

english, 1995

7

Molecular, Biological, and Preliminary Structural Analysis of Recombinant Bryodin 1, a Ribosome-Inactivating Protein from the Plant Bryonia dioica

Gawlak, Susan L., Neubauer, Michael, Klei, Herbert E., Chang,, Einspahr, Howard M., Siegall, Clay B.

Journal:

Year:

1997

Language:

english

File:

PDF, 341 KB

english, 1997

8

Properties of chimeric toxins with two recognition domains: interleukin 6 and transforming growth factor .alpha. at different locations in Pseudomonas exotoxin

Kreitman, Robert J., Siegall, Clay B., Chaudhary, Vijay K., FitzGerald, David J., Pastan, Ira

Journal:

Bioconjugate Chemistry

Year:

1992

Language:

english

File:

PDF, 1.99 MB

english, 1992

9

Characterization of Ribosome-Inactivating Proteins Isolated from Bryonia dioica and Their Utility as Carcinoma-Reactive Immunoconjugates

Siegall, Clay B., Gawlak, Susan L., Chace, Dana, Wolff, Edith A., Mixan, Bruce, Marquardt, Hans

Journal:

Bioconjugate Chemistry

Year:

1994

Language:

english

File:

PDF, 1.37 MB

english, 1994

10

Basic fibroblast growth factor-Pseudomonas exotoxin chimeric proteins; Comparison with acidic fibroblast growth factor-Pseudomonas exotoxin

Gawlak, Susan L., Pastan, Ira, Siegall, Clay B.

Journal:

Bioconjugate Chemistry

Year:

1993

Language:

english

File:

PDF, 1.42 MB

english, 1993

11

Identification of a specific tyrosine residue in Bryodin 1 distinct from the active site but required for full catalytic and cytotoxic activity

Daniel K. Fryxell, Susan L. Gawlak, Robert W. Dodge, Clay B. Siegall

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 2.74 MB

english, 1998

12

Targeted toxins as anticancer agents

Clay B. Siegall

Journal:

Year:

1994

Language:

english

File:

PDF, 717 KB

english, 1994

13

O-150 A phase II study of SGN-15 (cBR96-doxorubicin immunoconjugate) combined with docetaxel in patients with advanced stage or metastatic non-small cell lung cancer (NSCLC)

Ross, Helen, Rudin, Charles M., Figlin, Robert A., Hart, Lowell, Rarick, Mark, Jacobs, Andrew, Grove, Laurie, Sandler, Andrew S., Siegall, Clay, Sing, Amy P.

Journal:

Year:

2003

Language:

english

File:

PDF, 188 KB

english, 2003

14

Single-Chain Immunotoxins Targeted to CD40 for the Treatment of Human B Lineage Hematologic Malignancies

Francisco, Joseph A., Siegall, Clay B.

Journal:

Leukemia and Lymphoma

Year:

1998

Language:

english

File:

PDF, 827 KB

english, 1998

15

Analysis of sequences in domain II of Pseudomonas exotoxin A which mediate translocation

Siegall, Clay B., Ogata, Masato, Pastan, Ira, FitzGerald, David J.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.78 MB

english, 1991

16

TGFα-PE40 inhibits non-small cell lung cancer growth

Muriel Draoui, Clay B. Siegall, David FitzGerald, Ira Pastan, Terry W. Moody

Journal:

Year:

1994

Language:

english

File:

PDF, 534 KB

english, 1994

17

Cytotoxicity of chimeric (human-murine) monoclonal antibody BR96 IgG, F(ab')2, and Fab' conjugated to Pseudomonas exotoxin

Siegall, Clay B., Gawlak, Susan L., Chin, Jeffrey J., Zoeckler, Mary E., Kadow, Kathleen F., Brown, Joseph P., Braslawsky, Gary R.

Journal:

Bioconjugate Chemistry

Year:

1992

Language:

english

File:

PDF, 1.68 MB

english, 1992

18

Selective tumor sensitization to taxanes with the mAb-drug conjugate cBR96-doxorubicin

Alan F. Wahl, Karen L. Donaldson, Bruce J. Mixan, Pamela A. Trail, Clay B. Siegall

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 311 KB

english, 2001

19

Betacellulin-Pseudomonas toxin fusion proteins bind but are not cytotoxic to cells expressing HER4; correlation of EGFR for cytotoxic activity

Mixan, Bruce, Cohen, Bruce D, Bacus, Sarah S, Fell, H Perry, Siegall, Clay B

Journal:

Year:

1998

Language:

english

File:

PDF, 383 KB

english, 1998

20

Differential enzymatic accessibilities of the 5′ and 3′ splice sites of β-globin pre-messenger RNA in splicing competent hela cell nuclear extract

Clay B. Siegall, Ajit Kumar

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 1.16 MB

english, 1988

21

In vivo activities of acidic fibroblast growth factor-Pseudomonas exotoxin fusion proteins

Siegall, Clay B., Gawlak, Susan L., Chace, Dana F., Merwin, June R., Pastan, Ira

Journal:

Bioconjugate Chemistry

Year:

1994

Language:

english

File:

PDF, 1.39 MB

english, 1994

22

Rational design of a chimeric toxin: an intramolecular location for the insertion of transforming growth factor .alpha. within Pseudomonas exotoxin as a targeting ligand

Kreitman, Robert J., Chaudhary, Vijay K., Siegall, Clay B., FitzGerald, David J., Pastan, Ira

Journal:

Bioconjugate Chemistry

Year:

1992

Language:

english

File:

PDF, 1.19 MB

english, 1992

23

Reconstituted U1 small nuclear ribonucleoprotein complex restores 5′ splice site cleavage activity

Clay B. Siegall, Timothy T. Hla, Ajit Kumar

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 1.85 MB

english, 1988

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